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J Dent Res 48(4): 559-567, 1969
© 1969 International and American Associations for Dental Research
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Role of Insulin in Body Growth and the Growth of Salivary and Endocrine Glands in Rats

FRANK T. Y. LIU 1 and HSIEN S. LIN 1

1 Department of Physiology, School of Dentistry, University of Missouri, Kansas City, Missouri 64110

Alloxan-induced diabetes in immature rats retarded body growth and growth of salivary and endocrine glands. In mature rats, atrophic changes in salivary glands and weight loss resulted. In proportion to dose levels, insulin treatments prevented the retardation of body growth and growth of salivary and endocrine glands in immature diabetic rats and prevented the defective changes of salivary glands and body weight loss in mature diabetic rats.

Submitted on October 20, 1968






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