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J Dent Res 48(4): 521-525, 1969
© 1969 International and American Associations for Dental Research
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Electron Microscopy of the Calciotraumatic Response in Rat Incisor Dentin and Bone to Parenteral and Oral Administration of Tetracycline

Z. ANTALOVSKÁ 1, V. MELKOVÁ 1, and V. SMUTNÁ 1

1 Department of Stomatology, Charles University, Hradec Králové, and Department of Stomatology, J. E. Purkynecaron University, Brno, Czechoslovakia

The submicroscopic structure of the calciotraumatic response to tetracycline was studied in the dentin, mandible, and femur of 14 young rats. In the dentin, the shape of the tubules became irregular, and the intertubular substance appeared spongy. Incomplete mineralization occurred within the growth zones of the mandible and femur. The severity of the response depended on the quantity of tetracycline bound in the calcifying tissue.

Submitted on June 17, 1968




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L. J. Brearley and J. R. Porteous
Characteristics and Caries Experience of Tetracycline-Affected Dentitions
Journal of Dental Research, May 1, 1973; 52(3): 508 - 516.
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