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J Dent Res 48(3): 396-409, 1969
© 1969 International and American Associations for Dental Research

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Quantitation of Enamel Demineralization Mechanisms: III. A Critical Examination of the Hydroxyapatite Model

WILLIAM I. HIGUCHI 1, NASIM A. MIR 1, PRAFULL R. PATEL 1, JOHN W. BECKER 1, and JOHN J. HEFFERREN 1

1 College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48104, and American Dental Association, Chicago, Illinois 60611

A physical model which assumes that hydroxyapatite is the thermodynamic governing phase for the acid dissolution-rate behavior of enamel has been critically examined theoretically and experimentally. Both enamel powder and synthetic hydroxyapatite initial dissolution-rate experiments were conducted under various conditions of acid-butler type and concentration, pH, and common ion concentrations.

Submitted on July 8, 1968







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