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J Dent Res 48(2): 307-309, 1969
© 1969 International and American Associations for Dental Research
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Evidence of Thyrocalcitonin in Guinea Pig and Its Effects on Maternal-Fetal Calcium Relationships

E. G. CRAWFORD JR. 1, C. D. GREESON 1, D. C. CHANDLER JR. 1, and J. W. BAWDEN 1

1 Department of Pedodontics and the Dental Research Center, School of Dentistry, University of North Carolina, Chapel Hill, North Carolina 27514

An extract of guinea pig thyroid gland produced a mild hypocalcemia indicative of the presence of thyrocalcitonin when administered intravenously to nongravid guinea pigs. Extract-induced hypocalcemia in gravid guinea pigs resulted in a rise in fetal plasma calcium values at the end of four hours.

Submitted on September 18, 1968






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