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J Dent Res 48(2): 192-195, 1969
© 1969 International and American Associations for Dental Research
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Changes in Submaxillary Gland Protein and Nucleic Acids after Ethionine Administration

J. A. THOMAS 1, W. MASON 1, and M. MAWHINNEY 1

1 Department of Pharmacology, Medical Center, West Virginia University, Morgantown, West Virginia 26506

Ethionine administration (300 or 600 mg/kg daily for 5 or 11 days) produced significant reductions in submaxillary protein levels in normal mice. These reductions were not observed in these same tissues obtained from castrated mice treated with testosterone. Ethionine-induced changes in submaxillary ribonucleic acid (RNA) were also evident.

Submitted on March 20, 1968






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