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J Dent Res 48(1): 83-92, 1969
© 1969 International and American Associations for Dental Research
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Effect of Ascorbic Acid on Guinea Pig Skin Collagen Synthesis: II. Neutral and Acid Soluble Collagens, Mucopolysaccharides, and Amino Acid Composition

VIRGINIA RICHMOND 1 and E. L. R. STOKSTAD 1

1 Department of Nutritional Sciences, University of California, Berkeley, California 94720

Scorbutic guinea pigs incorporated approximately 15% as much 3H-proline into total skin collagen as the positive controls and hydroxylated 66% as much of that incorporated. 35S-sulfate incorporation into skin acid mucopolysaccharides was decreased 50% in scorbutic animals. Amino acid composition of collagens was similar to that of other vertebrates.

Submitted on June 24, 1968






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