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J Dent Res 47(5): 733-736, 1968
© 1968 International and American Associations for Dental Research

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Acquisition of Fluoride in Vivo by Enamel from Repeated Topical Sodium Fluoride Applications in a Fluoridated Area: A Preliminary Report

JAMES R. MELLBERG 1, CLYDE R. NICHOLSON 1, BARRY G. MILLER 1, and HAROLD R. ENGLANDER 1

1 Davies, Rose Hoyt Pharmaceutical Division, The Kendall Company, Barrington, Illinois; Central Piedmont Community College, Charlotte, North Carolina; and US Department of Health, Education, and Welfare, US Public Health Service, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland

Fluoride acquisition by deciduous enamel of 11- to 14-year-old children, living in a fluoridated area, was studied during repeated topical applications of acidulated phosphate fluoride gel drops in plastic mouthpieces. Enamel fluoride progressively increased as the number of treatments increased, reaching a concentration of 1,785 ppm at a depth of 5µ after an average of 56 treatments.

Submitted on February 5, 1968







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