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J Dent Res 47(5): 704-709, 1968
© 1968 International and American Associations for Dental Research
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Development of Caries in the Hunt-Hoppert Caries-Susceptible and Caries-Resistant Rats Under Different Experimental Conditions

RACHEL H. LARSON 1, PAUL H. KEYES 1, and BETTE JOAN GOSS 1

1 US Department of Health, Education, and Welfare, Public Health Service, National Institute of Dental Research National Institutes of Health, Bethesda, Maryland

Rats of both Hunt-Hoppert lines, originally designated as caries-susceptible (Ca-S) and caries-resistant (Ca-R) lines, were highly susceptible to caries when subjected to a combination of diet and microflora that provided a challenge to the resistance of all surfaces of the teeth. Strain differences were indicated by the predominance of sulcal lesions in the Ca-S line and smooth-surface lesions in the Ca-R line.

Submitted on November 22, 1967






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