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J Dent Res 47(3): 478-481, 1968
© 1968 International and American Associations for Dental Research
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Diurnal Variation in Deoxyribonucleic Acid Synthesis in Selected Epithelial Tissues of Male Rats

MARSHALL C. ENGLAND JR. 1 and GEORGE W. BURKE JR. 1

1 School of Dentistry, Medical College of Virginia, Richmond, Virginia

Thymidine-3H, 125µc, was injected intravenously into each of 11 male rats. The rats were killed one hour after injection, at fourhour intervals during a 24-hour period. Epithelial specimens were separated from the underlying connective tissue and subjected to liquid scintillation. The results indicated that maximal DNA synthesis occurred at 4:30 to 8:45 AM and that minimal synthesis occurred at 3:40 to 8:30 PM.

Submitted on November 20, 1967






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