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J Dent Res 47(2): 306-310, 1968
© 1968 International and American Associations for Dental Research
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Reactivity of Blood Group Substances of Neoplastic Oral Epithelium

RICHARD C. PRENDERGAST 1, PATRICK D. TOTO 1, and ANTHONY W. GARGIULO 1

1 Loyola University School of Dentistry, Chicago College of Dental Surgery, Chicago, Illinois

Histologic sections of 15 biopsy samples of normal oral mucosa and 8 biopsy samples of malignant oral carcinoma from patients with A, B, or AB blood groups were treated with anti-A or anti-B human antiserum and then with fluorescein isothiocyanate-bound goat antihuman globulin. Normal cells fluoresced intensely. Fluorescence of malignant cells was diminished or lost.

Submitted on September 6, 1967






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