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J Dent Res 47(2): 272-274, 1968
© 1968 International and American Associations for Dental Research

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Carbon 14 Tryptophan Metabolism in Developing Rat Molars

HAROLD C. SLAVKIN 1, C. E. TETREAULT 1, and LUCIEN A. BAVETTA 1

1 Department of Biochemistry, School of Dentistry, University of Southern California, Los Angeles, California

The unique absence of tryptophan in dentin collagen and its presence in enamel protein(s) provide a specific biological marker for the study of amelogenesis. Isotopic tryptophan was administered to young rats. The incorporation, distribution, and turnover of the labeled precursor was expressed in auto-radiographs and radiochemically determined specific activity.

Submitted on August 2, 1967







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