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J Dent Res 47(1): 127-138, 1968
© 1968 International and American Associations for Dental Research
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Hereditary Basis of Caries Resistance in Rats

C. K. CHAI 1, H. R. HUNT 1, C. A. HOPPERT 1, and S. ROSEN 1

1 The Jackson Laboratory, Bar Harbor, Maine; Michigan State University, East Lansing, Michigan, and Ohio State University, Columbus, Ohio

Lines of rats susceptible and resistant to dental caries were produced through 25 and 19 generations of breeding, respectively. Differences in mean caries time between the two lines were found to be as great as more than 500 days in some late generations. Heritability estimates yielded values of 0.40 and 0.62.

Submitted on July 17, 1967






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