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1 Departments of Histology and Pedodontics, School of Dentistry, University of Buenos Aires, Argentina
Sixty white rats were divided into three groups: Group I, control; Group II, mesial root canal of the first lower molar treated and filled with zinc oxide-eugenol; Group III, treatment as in Group II and distal exposure to produce infection to the residual pulp and periapical complications.
Five rats of each group were sacrificed 15, 30, 60, and 90 days after treatment, and buccolingual sections were made at the level of the mesial root. The histometric study of the sections showed that the periapical complications of the untreated vestibular, lingual, and distal roots produce additional osteosclerosis at the level of the treated mesial root.
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