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J Dent Res 45(4): 993-997, 1966
© 1966 International and American Associations for Dental Research
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Effect of Passive Immunization on the Dental Caries Incidence of Caries-Susceptible Rats

E. A. SWEENEY 1, J. H. SHAW 1, and E. L. CHILDS 1

1 Harvard School of Dental Medicine, Boston, Massachusetts

Passive immunization of a caries-susceptible strain of rats by means of a gamma globulin preparation from the serum of caries-resistant rats was ineffective in reducing the amount of dental decay in the immunized animals.

Injected radioiodinated gamma globulin, which was also contaminated by some albumin and beta globulin, was detected in small amounts in corresponding positions on the electrophoretic patterns of whole saliva from these animals.

Submitted on June 10, 1964






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