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J Dent Res 44(1): 96-98, 1965
© 1965 International and American Associations for Dental Research
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The Effect of Adrenalectomy and Cortisone Supplementation on Caries Incidence in Caries-susceptible Rats

E. A. SWEENEY 1 and J. H. SHAW 1

1 Harvard School of Dental Medicine, Boston, Massachusetts

Contrary to a previous report, adrenalectomy did not increase the caries susceptibility of our caries-susceptible strain of rat. Animals receiving salt supplementation of the diet and drink demonstrated a trend toward lower scores for third molars only. Intact rats receiving 0.6 mg. cortisone per day exhibited a trend toward higher scores of borderline significance, which was not seen in the adrenalectomized rats also receiving cortisone.

Submitted on January 27, 1964






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