Reactions of NaF and SnF₂ with Dental Enamel Having Varying Ca:P Ratios

¹ Department of Biochemistry, Indiana University Medical Center, Indianapolis, Indiana

Studies were designed to determine whether different diets varying in their Ca:P contents could modify the resistance of the surface structure of enamel to acid solubility following the topical treatment of the erupted teeth with either NaF or SnF₂. When diets with a Ca:P ratio of 10:1 were fed to either weanling rats or to adult rats, the initial effectiveness and duration of effectiveness of topically applied SnF₂ was much greater than when similar rats received a diet with a Ca:P ratio of 1:10. The reactions resulting from the topical application of NaF to rat dental enamel did not appear to be similarly affected by changes in the Ca:P ratio of the diet. The data further suggested that as the Ca:P ratio of the enamel increased, the effectiveness of topically applied SnF₂ increased.

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