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J Dent Res 43(4): 563-567, 1964
© 1964 International and American Associations for Dental Research

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Distribution of Ca45 during Pregnancy under Conditions of Calcium Deficiency in Rats

JAMES W. BAWDEN 1 and F. THOMAS McIVER 1

1 Department of Pedodontics, University of North Carolina, Chapel Hill, North Carolina

Fifty-three pregnant Sprague-Dawley rats were studied with respect to the distribution of dietary Ca45 under conditions of calcium deficiency as compared with control conditions. In contrast to a previous study, the animals were sacrificed 1 hour after administration of the tracer. This was done to prevent mobilization of Ca45, which had entered the skeletons of the maternal animals, from contributing to the maternal-fetal distribution pattern of dietary Ca45. Results supported previous findings that the placenta is not capable of compensation in the face of calcium deficiency.

Submitted on August 19, 1963




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Endocr. Rev.Home page
C. S. Kovacs and H. M. Kronenberg
Maternal-Fetal Calcium and Bone Metabolism During Pregnancy, Puerperium, and Lactation
Endocr. Rev., December 1, 1997; 18(6): 832 - 872.
[Abstract] [Full Text]




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