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J Dent Res 43(1): 26-34, 1964
© 1964 International and American Associations for Dental Research
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Osteogenic Activity Following Bone and Sponge Implantation

CHARLES E. BARR 1, JOHN J. SALLEY 1, and RICHARD A. LeHEW 1

1 Department of Dental Research, Medical College of Virginia School of Dentistry, Richmond, Virginia

The role of despeciated embryonic bovine bone and polyvinyl sponge* implants was studied in femur defects in 30 guinea pigs. They were compared in healing rate with control wounds containing no implants.

The implants initially served as a deterrent to some degree, and there was a lag in the formation of new tissue as compared to the controls. By 5 weeks, however, all defects were bridged, and by 8 weeks, though complete healing was seen, the sponge and bone were not completely removed, but were incorporated into the newly formed bone.

Submitted on November 19, 1962






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