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J Dent Res 42(6): 1400-1404, 1963
© 1963 International and American Associations for Dental Research
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Effects of Adrenalectomy upon Ascorbic Acid Concentration in Periodontal Tissues in Guinea Pigs

JORGE A. KOFOED 1, ALBERTO B. HOUSSAY 1, CARLOS E. BOZZINI 1, and MARIA E. BARRIO RENDO 1

1 Department of Physiology, School of Dentistry, University of Buenos Aires, Buenos Aires, Argentina

The concentration of ascorbic acid in the testicles, adrenals, pituitary, plasma, gingiva, periosteum, and periodontium of bilaterally and unilaterally adrenalectomized guinea pigs was determined using the method of Roe and Kuether.11

Bilaterally adrenalectomized guinea pigs showed a decrease in ascorbic acid concentration in the testicles, plasma, gingiva, periosteum, and periodontium. No changes in pituitary ascorbic acid levels were observed.

In unilaterally adrenalectomized guinea pigs an increase in ascorbic acid concentration was observed in the testicles, adrenal glands, pituitary, plasma, periosteum, and periodontium. No changes in the gingiva were seen.

Submitted on November 26, 1962






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