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J Dent Res 42(3): 835-841, 1963
© 1963 International and American Associations for Dental Research
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Systemic Factors That Influence the Manifestations of Osteolathyrism in the Periodontium

IRVING GLICKMAN 1, HANS SELYE 1, and JEROME B. SMULOW 1

1 Ziskin Memorial Research Laboratory, Department of Periodontology, Tufts University School of Dental Medicine, Boston, Massachusetts

Systemic conditioning agents modified the severity of osteolathyritic changes induced in the periodontium of albino rats by administration of 10 mg of AAN/day. The lathyritic manifestations in the periodontium were accentuated by partial hepatectomies, thyroparathyroidectomy and thyroparathyroidectomy plus thyroxin (1 µg/day) and reduced by ACTH (10 I.U./day) and almost completely nullified by thyroxin (500 µg/day).

Submitted on September 12, 1962






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