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J Dent Res 42(2): 732-738, 1963
© 1963 International and American Associations for Dental Research
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Systemic Phosphate Influences on Dental Caries in the NMRI-D Rat

CARL A. OSTROM 1 and ROBERT VAN REEN 1

1 Dental Division, Naval Medical Research Institute, National Naval Medical Center, Bethesda 14, Maryland

Using a standardized experimental schedule (a basal purified diet, 35-day experimental period, and rats caged singly) which produces only pit-and-fissure caries in the NMRI-D rat, daily intubation of phosphate buffer, in amounts equivalent to that received on a diet supplemented with 1.5 and 3.0 per cent Na2HPO4, showed no detectable cariostatic activity.

Submitted on September 18, 1962




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F. J. McClure
Cariostatic Effect of Phosphates
Science, June 12, 1964; 144(3624): 1337 - 1338.
[Abstract] [PDF]


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