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J Dent Res 41(3): 707-712, 1962
© 1962 International and American Associations for Dental Research
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Studies on the Anticariogenic Activity of Oat Hulls

JAMES J. VOGEL 1, DAVID J. THOMPSON 1, and PAUL H. PHILLIPS 1

1 Department of Biochemistry, University of Wisconsin, Madison, Wisconsin

The anticariogenic activity extractable from oat hulls was found to be associated with the acidic fraction of the ether-solubles. This fraction contained fatty acids, several phenolic acids, and at least three polyphenols. Neither the fatty acids, palmitic and oleic, nor the phenolic acids gave any reduction in caries when tested individually. A correlation between the polyphenols and the anticariogenic activity was found. Three polyphenols were identified as the following flavonoids: tricin, homoeriodictyol, and the chalcone of homoeriodictyol. Attempts to separate these compounds and test them individually are now in progress.

Submitted on October 5, 1961




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F. J. McClure
Cariostatic Effect of Phosphates
Science, June 12, 1964; 144(3624): 1337 - 1338.
[Abstract] [PDF]


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