Absorption of Fluoride by the Gastric Mucosa in the Rat

¹ Department of Biochemistry, Baylor University College of Dentistry, Dallas, Texas

The gastric mucosa were shown to be capable of efficient absorption of trace amounts of fluoride when introduced directly into the ligated stomach. The plot of residual fluoride versus time was a complex curve, with both a lag in absorption initially and an appreciable retention of fluoride beyond 5 hours. The characteristics of the fluoride disappearance curve and the absorption rates derived from it should be considered of most value in a comparison of the absorption capacities of various segments of the gastrointestinal tract.