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J Dent Res 40(6): 1112-1115, 1961
© 1961 International and American Associations for Dental Research
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The Principle of Bacterial Antagonism Applied as an Aid in the Reduction of Dental Caries

RICHARD R. RUTTER 1, WALTER G. RUEFENACHT 1, CLOYD R. CHAMBERLAIN 1, PAUL R. THOMASSEN 1, MARIAN ROSE 1, and CHARLES A. SCRIVENER 1

1 College of Physicians and Surgeons of San Francisco, California

A strain of B. brevis with known in vitro inhibition to the growth of oral acidogenic micro-organisms was introduced into the mouths of 46 human volunteers. A group of 101 persons served as controls. The incidence of dental caries was reduced by 50 per cent in the experimental group.

Submitted on May 2, 1960






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