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1 Department of Dental Science, Royal College of Surgeons, London
Micro-organisms cultured from calculus and carious dentin demonstrated a similar phosphatase activity over a wide pH range with peaks at pH 5.5 and 8.5. Sodium [see figure in the PDF file] fluoride inhibited enzyme activity in concentrations of 101-104 M. Results suggest that microbial phosphomonoesterase is not specifically concerned in calculus formation.
This work was carried out during the tenure of a Quintin Hogg Fellowship in the Department of Dental Science at the Royal College of Surgeons. I am grateful to Mr. E. B. Brain for preparing the illustrations.
Submitted on November 4, 1960
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