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1 Department of Biochemistry and Zoller Memorial Clinic, University of Chicago
Microradiographic studies with a Phillips contact microradiographic unit (CMR-5) were made of both early and advanced zones of white-spot smooth-surface lesions in longitudinal and transverse section.
These studies show that carious demineralization begins at the periphery of the rod, then involves the cross-striations, striae of Retzius, and prism body, leaving the interprismatic substance largely undemineralized until last.
Submitted on June 27, 1960
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