Combined Anticariogenic Effect of a Single Stannous Fluoride Solution and the Unsupervised Use of a Stannous Fluoride-containing Dentifrice II. Results at the End of Two Years
JOSEPH C. MUHLER 1
1 Department of Biochemistry, Indiana University Medical Center, Indianapolis, Indiana
The routine use of a commercially available stannous fluoride-containing dentifrice in those subjects who receive a single application of an 8 per cent solution of stannous fluoride each 6 months was associated with a significant reduction in dental caries. This anticariogenic effect did not decrease in magnitude during a 2-year study period.
Submitted on December 17, 1959
Revised on March 8, 1960
