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J Dent Res 39(2): 267-272, 1960
© 1960 International and American Associations for Dental Research
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Endotoxic Properties of Oral Bacteria as Revealed by the Local Shwartzman Reaction

STEPHAN E. MERGENHAGEN 1

1 National Institute of Dental Research, National Institutes of Health, Public Health Service, U.S. Department of Health, Education, and Welfare, Bethesda 14, Maryland

Tryptic digestion of acetone-dried Gram-negative oral bacteria (Veillonella, Fusobacterium) released soluble endotoxins, which elicited hemorrhagic and necrotic lesions in the rabbit (Shwartzman reaction). Oral diphtheroid bacilli and anaerobic streptococci did not yield Shwartzman-reactive endotoxins after similar treatment.

Submitted on July 22, 1959
Revised on November 23, 1959






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