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J Dent Res 39(2): 205-214, 1960
© 1960 International and American Associations for Dental Research
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The Localization of Microörganisms in Inflamed Dental Pulps of Rats Following Bacteremia

GEORGE W. BURKE JR. 1 and HOLMES T. KNIGHTON 1

1 Department of Dental Research, Medical College of Virginia, Richmond, Virginia

The pulps of 993 rat molars were analyzed for bacterial content following intravenous injection of S. aureus. Exposed and non-exposed pulps were studied with a variety of filling materials and variations in the time of sacrifice and injection of the test organism. Bacterial localization occurred more frequently among exposed pulps. When the time of injection or the date of sacrifice was delayed, the incidence of bacterial localization was reduced in all series except croton-oil-treated exposures. This study is accompanied by a statistical and histopathologic analysis.

Submitted on October 27, 1959
Revised on December 7, 1959




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