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1 Department of Biochemistry, Indiana University, Indiana University Medical Center, Indianapolis, Ind.
A total of 751 children, ages 6 to 16 years, were divided into three groups in order to test the anticariogenic effectiveness of a SnF2 dentifrice and a combination of topically applied SnF2 and a SnF2 dentifrice. The results after 6 and 12 months showed approximately 30 per cent less tooth decay in the group using the SnF2 dentifrice alone when the DMFT index was used, and approximately 20 per cent less new dental caries when the DMFS index was used. When the combination of topical and SnF2 dentifrice was used, approximately 60 per cent less new caries was found after 6 and 12 months by using either the DMFS or the DMFT index. It is suggested that, in order to obtain the maximum anticariogenic effect from the topical SnF2 application or the SnF2 dentifrice, both be used in conjunction with each other.
Submitted on March 26, 1959
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