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J Dent Res 38(1): 149-155, 1959
© 1959 International and American Associations for Dental Research
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ANALYSIS OF AN ANOMALOUS OCULODENTOFACIAL PATTERN IN NEWBORN RATS PRODUCED BY MATERNAL HYPERVITAMINOSIS A

FREDERICK M. DEUSCHLE 1, JEAN F. GEIGER 1, and JOSEF WARKANY 1

1 Departments of Anatomy and Pediatrics, and the Children's Hospital, Research Foundation, College of Medicine, University of Cincinnnati, Cincinnati, Ohio

Oculodentofacial anomalies observed in the young of rats with hypervitaminosis A were analyzed. It was found that exophthalmic eyes were essentially normal in structure but protruded as a result of congenital malformation of the orbital floor. Anomalies of the maxilla and the molar teeth were also seen. These anomalies were different from those produced by maternal riboflavin deficiency previously described.

Submitted on July 21, 1958






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