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1 Harvard School of Dental Medicine, Boston, Mass.
The rate of growth of male and female sialoadenectomized rats was much less than that of their normal littermates.
The total food consumption and the food consumption per gram of body weight increase were greater for sialoadenectomized rats than for normal littermates.
The water consumption of sialoadenectomized rats from a caries-susceptible strain was greater than the water consumption of the control littermates.
Sialoadenectomy caused major increases in dental caries incidence in rats from a highly caries-resistant strain as well as in rats from a highly caries-susceptible strain. The rats from the caries-susceptible strain continued to demonstrate a higher caries-susceptibility after sialoadenectomy than operated rats from the caries-resistant strain. The increased caries initiation and progression was as evident in the maxillary molars as in the mandibular molars of both strains.
Submitted on January 20, 1958
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