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1 Department of Preventive Dentistry, University of Otago, Dunedin, New Zealand, and Eastman Dental Dispensary, Rochester, N. Y.
Osborne-Mendel strain rats were placed on a cariogenic diet until dental caries was detected in the occlusal surfaces of lower first or second molars. They were then assigned to different groups for a specified length of time to determine the effect of sucrose in various forms on the rate of spread of established lesions.
The results suggest that there is no difference between the effect on the spread of caries of sucrose in aqueous solution and sucrose in solid form. But when sucrose was fed in the form of a carbonated beverage and as a dilution of orange juice concentrate, dental caries progressed at a significantly slower rate.
Submitted on May 19, 1957
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