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J Dent Res 37(2): 326-329, 1958
© 1958 International and American Associations for Dental Research

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FLUORIDE PLACENTAL TRANSFER IN THE RAT

G. BUTTNER PH.D.1 and JOSEPH C. MUHLER D.D.S., PH.D.1

1 Indiana University, Bloomington, Ind.

A total of 7 groups of rats received different amounts of fluoride in the drinking water during pregnancy and lactation. The skeletal fluoride storage of the pups was determined. These data indicate that drinking water at a concentration of 10 ppm F must be received by the mother before any appreciable increase in carcass fluoride is found in the pups. Data are presented which indicate a mammary gland transfer, especially at higher fluoride levels.

Submitted on May 15, 1957
Revised on November 26, 1957







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