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1 Department of Pathology, School of Dentistry, Medical College of Virginia, Richmond, Va.
A study has been described wherein 50 albino hamsters of weanling age were divided into three groups. One group was placed on a synthetic diet including all the known required nutritional elements with the exception of vitamin A. The other two groups served as controls. The deficient group exhibited marked changes in the salivary glands, respiratory mucosa, odontogenic tissues, and the gonads. These changes were characterized principally by metaplasia of various epithelia to a squamous type. The possibility of the use of the hamster in chronic vitamin A deficiency studies has been discussed, and a comparison has been made of histopathologic findings of avitaminosis A in this species to other animals suffering from the same deficiency.
Submitted on April 11, 1957
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D. G. Kaufman, M. S. Baker, J. M. Smith, W. R. Henderson, C. C. Harris, M. B. Sporn, and U. Saffiotti RNA Metabolism in Tracheal Epithelium: Alteration in Hamsters Deficient in Vitamin A Science, September 22, 1972; 177(4054): 1105 - 1108. [Abstract] [PDF] |
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TOOTH DEVELOPMENT (continued from page 116) The Journal of the Royal Society for the Promotion of Health, March 1, 1965; 85(2): 127 - 127. |
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