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J Dent Res 36(5): 709-712, 1957
© 1957 International and American Associations for Dental Research
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THE EFFECT OF SEX HORMONES ON DENTAL CARIES IN DESALIVATED RATS

DAVID BIXLER 1, JOSEPH C. MUHLER 1, and WILLIAM G. SHAFER 1

1 Indiana University, Bloomington, Ind., and Indianapolis, Ind.

Injection of either estradiol or testosterone into castrated animals restored the dental caries incidence to the control level. Similarly, the injection of these hormones into castrated and salivariadenectomized rats restored the caries incidence to the same high level found in salivariadenectomized rats. These results indicate that the major salivary glands are probably not important intermediates in a sex hormone-dental caries relationship in the rat.

Submitted on August 11, 1956






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