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J Dent Res 36(4): 576-580, 1957
© 1957 International and American Associations for Dental Research

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ENLARGEMENT OF SUBMANDIBULAR SALIVARY GLANDS OF RATS RESTRICTED TO ACIDIC AND BASIC SOLUTIONS AS THE SOLE SOURCE OF DRINKING FLUID

GERALD J. COX 1, WILLARD G. CLEMENTS 1, EDWARD C. HILGER JR. 1, and DAVID W. DEGRANGE 1

1 Research Department, School of Dentistry, University of Pittsburgh, Pittsburgh, Pa.

The submandibular salivary glands of rats were significantly enlarged when the sole drinking fluid was unbuffered 0.05 molar acetic, lactic, citric, tartaric, or phosphoric acid, during the period 21 to 49 days of age, comparison being made with the glands of littermate rats with water to drink. No increase in size of the glands was caused by 0.05 molar sodium bicarbonate or oxalic acid.

Submitted on July 21, 1956







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