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J Dent Res 36(3): 403-408, 1957
© 1957 International and American Associations for Dental Research
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EFFECT OF HORMONES ON STRUCTURE AND PROTEOLYTIC ACTIVITY OF SALIVARY GLANDS

PATRICIA G. CLARK 1, WILLIAM G. SHAFER 1, and JOSEPH C. MUHLER 1

1 Indiana University, School of Dentistry, Department of Oral Pathology and Department of Chemistry, Indianapolis and Bloomington, Ind.

It has been shown that the proteolytic activity of the rat submaxillary gland is increased by the administration of desiccated thyroid and decreased by propylthiouracil. This alteration in activity occurs concomitantly with histologic changes in the gland.

Hypophysectomy prevents the morphologic development of this gland and in addition suppresses the proteolytic activity. This could not be prevented by the administration of either desiccated thyroid or testosterone alone or in combination.

Submitted on January 10, 1956






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