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J Dent Res 36(2): 166-172, 1957
© 1957 International and American Associations for Dental Research
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FURTHER STUDIES ON THE INFLUENCE OF SURFACE ACTIVE AGENTS ON DECALCIFICATION OF THE ENAMEL SURFACE

M. IRWIN 1, A. G. LEAVER 1, and J. P. WALSH 1

1 University of Otago Dental School, Dunedin, New Zealand

1. The investigation of the effectiveness of surface active agents in inhibiting calcium dissolution has been continued.

2. In a preliminary experiment some 20 compounds were tested for their ability to reduce the dissolution of calcium phosphate by an acid buffer at pH 4.0.

3. Four of the compounds were tested for their ability to protect the enamel surface against the solvent action of the same buffer.

4. It was found that the straight chain primary amines were the most effective agents of those tested. Previous results indicating that tetradecylamine was the most successful of the aliphatic amines available commercially were confirmed.

5. It was found that pentadecylamine, synthesized in this laboratory, exhibited a slightly higher protective capacity than the commercial tetradecylamine, whether as the water soluble acetate, in oil solution, or in an emulsion dentifrice.

Submitted on December 10, 1955






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