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1 The Department of Chemistry, Indiana University, Bloomington, Ind.
The method of Muhler, Boyd, and Van Huysen7 for the evaluation of the effectiveness of substances in reducing enamel solubility has been modified to include 3 successive decalcifications of enamel subsequent to treatment with a protecting solution. This modified procedure makes the evaluations more critical than the original method which involves only 1 decalcification.
The data presented lead to the conclusion that the protection afforded enamel by sodium fluoride and stannous fluoride is a function of the pH at which the fluoride is applied, with the greatest effectiveness appearing at low pH levels and with stannous fluoride solutions.
Submitted on August 25, 1955
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