A STUDY OF INFERIOR ALVEOLAR NERVE BLOCK ANESTHESIA IN HUMANS COMPARING 2.0 PER CENT PROCAINE WITH 2.0 PER CENT PROCAINE PLUS 1:50,000 EPINEPHRINE

¹ Department of Dentistry, University of Rochester, School of Medicine and Dentistry, and The Eastman Dental Dispensary, Rochester, N. Y.

1. Fifty medical students received right inferior alveolar nerve blocks of 2.0 per cent procaine solution with and without 1:50,000 epinephrine.

2. The subjects were observed for changes in pulse rate, blood pressure, pulse pressure, respiratory rate; sign of tremor, sweating, and faintness; and onset, duration, and quality of anesthesia and postanesthetic pain.

3. Procaine-ephinephrine injection resulted in the following statistically significant differences as compared to plain procaine: (a) drop in postinjection diastolic blood pressure, (b) longer duration of anesthesia, (c) increased number of untoward reactions, and (d) more desirable depths of anesthesia.