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J Dent Res 35(4): 615-619, 1956
© 1956 International and American Associations for Dental Research

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DECREASED ACTIVITY OF DENTAL CARIES IN DESALIVATED ALBINO RATS

JOSEPH C. MUHLER 1 and DAVID BIXLER 1

1 Indiana University, Bloomington, Ind.

The removal of all maxillary molars prevented the development of dental caries in the mandibular teeth of albino rats receiving a cariogenic stock corn diet, thus indicating the importance of the complete dentition for dental caries initiation and progression. The removal of the major salivary glands did not significantly increase the dental caries experience in the absence of the maxillary molars even though the rats received a cariogenic diet. In desalivated rats which have their maxillary molars present but which are receiving a high sucrose diet, only a small degree of dental caries results. These findings suggest that desalivation per se has little influence on the development of dental caries in the albino rat in the absence of initiating factors.

Submitted on February 16, 1955







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