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J Dent Res 35(4): 591-595, 1956
© 1956 International and American Associations for Dental Research
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PRECISION OF SALIVARY SEDIMENT TECHNIC FOR EVALUATING INHIBITORS

G. L. HARGREAVES 1 and R. S. MANLY 1

1 Tufts University School of Dental Medicine, Boston, Mass.

A test of reproducibility has been made for the salivary sediment method1 of measuring the influence of inhibitors on acid formation rates. The standard deviation of a single determination from the mean was found to range from 5 to 20 per cent, depending on the method used in preparing the sediment and the type of chemical being tested. An over-all standard deviation of duplicates from their means was 7 per cent. Higher concentrations of inhibitory agents are required to inhibit acid formation in salivary sediment than are needed to inhibit acid formation in saliva-glucose mixtures.

Submitted on January 14, 1955






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