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1 Loyola University College of Dentistry; College of Dentistry, University of Illinois; and College of Pharmacy, University of Illinois, Chicago, Ill.
Changes in the gingival connective tissues during pregnancy have been demonstrated using an electrometric method. The density of negatively charged colloid, including the glycoproteins of the ground substance, was decreased in the early months of pregnancy. The tissues were restored to the normal state several months after parturition. The connective tissue alterations, present in almost all patients studied, were often unaccompanied by any clinical signs. This response of the gingiva is an example of the sensitivity of oral tissues to hormones or other somatic influences.
Submitted on February 15, 1955
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