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1 Fels Research Institute, Antioch College, Yellow Springs, Ohio
1. The sequence of calcification of the mandibular molar and premolar teeth was investigated in serial oblique-jaw x-rays of 359 native-born white children from southwestern Ohio.
2. M1 P1 and M3 invariably showed initial calcification first, second, and last, respectively. P2 and M2 calcification varied in the order of appearance, and in many cases these teeth began to calcify at the same time.
3. In the girls the tendency for P2 to precede M2 was more marked. The boys, however, tended to the (P2 M2) sequence, thus exhibiting "bunching" in tooth calcification as they are known to do in tooth emergence.
4. Among 191 boys and girls, the M1 P1 P2 M2 M3 sequence was observed in 40.3 per cent, the M1 P1 (P2 M2) M3 sequence in 37.7 per cent, and the M1 P1 M2 P2 M3 sequence in 21.9 per cent.
5. Siblings of P2 M2 children tended to the P2 M2 sequence and siblings of M2 P2 children to the M2 P2 sequence more often than would be expected on a chance basis.
6. It was suggested that there has been a gradual evolutionary change from the M2 P2 sequence in the direction of the P2 M2 sequence, with a different rate of evolution in different hominid groups.
Submitted on February 2, 1955
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