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J Dent Res 34(5): 661-665, 1955
© 1955 International and American Associations for Dental Research
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EXPERIMENTAL DENTAL CARIES

VII. THE EFFECT OF VARIOUS ANDROGENS AND ESTROGENS ON DENTAL CARIES IN THE RAT

JOSEPH C. MUHLER 1 and WILLIAM G. SHAFER 1

1 Department of Chemistry and School of Dentistry, Indiana University, Bloomington and Indianapolis, Ind.

Two androgens (testosterone and methylandrostenediol) and estrogens (estradiol and diethylstilbestrol) affect the dental caries incidence in immature rats in a different manner. In unoperated animals the androgens are without effect in altering the normally experienced caries rate, while the estrogens significantly increase the incidence of dental caries. When the animals are gonadectomized and then receive the different hormones, no difference is noticed by androgen administration, while the effect of the estrogens appears to be more pronounced.

Submitted on April 24, 1954






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