JDR JDR Most Cited Articles
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Dent Res 34(4): 478-488, 1955
© 1955 International and American Associations for Dental Research
This Article
Right arrow Full Text (PDF)
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by BISHOP, J. G.
Right arrow Articles by MUHLER, J. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by BISHOP, J. G.
Right arrow Articles by MUHLER, J. C.

THE EFFECT OF DIFFERENT FLUORIDES ON VASCULAR TONE AND ALTERATION IN THE RATE OF BLOOD FLOW

JACK G. BISHOP 1, ALFRED W. RICHARDSON 1, and JOSEPH C. MUHLER 1

1 Indiana University, Department of Physiology and Department of Chemistry, Bloomington, Ind.

1. Fluorine added to the blood acts as a vasodilator. Flow increases may be elicited by 0.15 mg. or more fluorine, and amounts in excess of 5 mg. result in a decline in blood pressure.

2. The cation of a fluoride compound influences its activity. The order of activity of 4 fluorides studied was SnF2, KF, Na2PO3F, and NaF.

3. The action of fluorine is longer than most vasodilators, and concomitant studies of respiration and muscle temperatures suggest that it may act to depress body cell metabolism, in the higher concentrations studied.

4. It is believed that these findings suggest a mechanism by which fluorine may stimulate the flow of saliva which has been reported but not well explained.

Submitted on April 10, 1954






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
IADR Journals Advances in Dental Research ®
Journal of Dental Research ® Critical Reviews (1990-2004)
Copyright © 1955 Institutional Access Guidelines