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J Dent Res 34(1): 68-72, 1955
© 1955 International and American Associations for Dental Research
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EFFECT OF pH AND STATE OF OXIDATION OF DIFFERENT FLUORIDES IN THE DRINKING WATER ON DENTAL CARIES AND FLUORINE STORAGE IN THE RAT

JOSEPH C. MUHLER 1 and HARRY G. DAY 1

1 Department of Chemistry, Indiana University, Bloomington, Ind.

When stannous fluoride and stannous chlorofluoride were given to rats fresh each day in oxygen-free drinking water at a fluorine concentration of 20 µg per milliliter and at pH 3.5, they were decidedly more effective in reducing the initiation and extension of dental caries than was sodium fluoride at the same pH. However, the marked effectiveness of these two tin fluorides is decreased when the pH is increased to 5.5, while sodium fluoride is not affected to the same degree.

The degree of dental caries resistance does not seem to be related to the storage of fluorine in the femur, and the pH of the fluoride solution apparently is not related to its storage.






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