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1 School of Dentistry and Department of Chemistry, Indiana University, Bloomington, Indiana, and College of Dentistry, Ohio State University, Columbus, Ohio
A stannous fluoride-containing dentifrice at a fluorine concentration of 1,000 ppm and a tin concentration of 3,200 ppm results in a pronounced redution in dental caries in 6- to 15-year-old children after using the dentifrice in an unsupervised manner for a period of six months. When compared to an identical control dentifrice not containing stannous fluoride, a 53 per cent reduction in DMF teeth and a 72 per cent reduction in DMF surfaces resulted. There appeared to be complete protection against interproximal lesions, while the reduction in buccal-lingual surfaces was 70 per cent and occlusal surfaces 26 per cent. All of the reductions are highly significant except the reduction in occlusal surfaces. The reduction of caries appears to be related to the subjects' ages, with the greatest protection occurring in the older age groups of the children. The effect of possible toxic effects through the continued use of a stannous fluoride dentifrice is discussed.
Submitted on August 14, 1953
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