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J Dent Res 33(4): 497-503, 1954
© 1954 International and American Associations for Dental Research
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CALCIFICATION

XI. STUDIES OF THE INCORPORATION OF CITRATE IN CALCIFICATION IN VITRO

ALBERT EDWARD SOBEL 1, HARRY GOLDENBERG 1, and EMANUEL SCHMERZLER 1

1 Department of Biochemistry, Jewish Hospital of Brooklyn, Brooklyn, N. Y.

The citrate:PO4 ratios of the new minerals deposited during calcification in vitro are related to the citrate:PO4 ratios of the fluid. This may be taken as further evidence for the hypothesis that variations of the composition of mineral deposits in the body are related to variations in composition of the fluid from which the deposits form. There was no evidence of citrate incorporation in the absence of citrate in the fluid, above the small amount of citrate initially present.

Submitted on July 6, 1953






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